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Stefan Schwabe Selected Research

Viloxazine

1/2022Impact of a High-Fat Meal and Sprinkled Administration on the Bioavailability and Pharmacokinetics of Viloxazine Extended-Release Capsules (QelbreeTM) in Healthy Adult Subjects.
12/2021Population Pharmacokinetics of Viloxazine Extended-Release Capsules in Pediatric Subjects With Attention Deficit/Hyperactivity Disorder.
11/2021Impact of Paroxetine, a Strong CYP2D6 Inhibitor, on SPN-812 (Viloxazine Extended-Release) Pharmacokinetics in Healthy Adults.
7/2021A Phase 3, Placebo-Controlled Trial of Once-Daily Viloxazine Extended-Release Capsules in Adolescents With Attention-Deficit/Hyperactivity Disorder.
2/2021Pharmacokinetics of Coadministered Viloxazine Extended-Release (SPN-812) and Methylphenidate in Healthy Adults.
1/2021Viloxazine in the Management of CNS Disorders: A Historical Overview and Current Status.
1/2021A Phase 3 Placebo-Controlled Trial of Once-Daily 400-mg and 600-mg SPN-812 (Viloxazine Extended-Release) in Adolescents with ADHD.
1/2021Once-Daily SPN-812 200 and 400 mg in the treatment of ADHD in School-aged Children: A Phase III Randomized, Controlled Trial.
1/2020New Insights into the Mechanism of Action of Viloxazine: Serotonin and Norepinephrine Modulating Properties.
1/2020A Phase II Double-Blind, Placebo-Controlled, Efficacy and Safety Study of SPN-812 (Extended-Release Viloxazine) in Children With ADHD.
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Stefan Schwabe Research Topics

Disease

14Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
01/2022 - 03/2019
3Epilepsy (Aura)
01/2020 - 07/2003
1Body Weight (Weight, Body)
12/2021
1Cardiotoxicity
01/2021
1Seizures (Absence Seizure)
01/2020
1Nausea
02/2004
1Paresthesia (Dysesthesia)
02/2004
1Migraine Disorders (Migraine)
02/2004
1Fatigue
02/2004

Drug/Important Bio-Agent (IBA)

11ViloxazineIBA
01/2022 - 01/2020
3Anticonvulsants (Antiepileptic Drugs)IBA
01/2020 - 01/2004
3Topiramate (Topamax)FDA LinkGeneric
02/2004 - 07/2003
2Molindone (Molindone Hydrochloride)FDA Link
01/2021 - 03/2019
1Norepinephrine Plasma Membrane Transport Proteins (Norepinephrine Transporter)IBA
02/2021
1Serotonin ReceptorsIBA
02/2021
1Antidepressive Agents (Antidepressants)IBA
01/2021
1Tricyclic Antidepressive Agents (Tricyclic Antidepressants)IBA
01/2021
1Monoamine Oxidase Inhibitors (Monoamine Oxidase Inhibitor)IBA
01/2021
1Pharmaceutical PreparationsIBA
10/2020
1Serotonin (5 Hydroxytryptamine)IBA
01/2020
1Norepinephrine (Noradrenaline)FDA LinkGeneric
01/2020
1Oxcarbazepine (Trileptal)FDA LinkGeneric
01/2020
1Lamotrigine (Lamictal)FDA LinkGeneric
07/2003

Therapy/Procedure

3Therapeutics
01/2020 - 07/2003